Gabriella Rasponi, widow of Count Venceslao Spalletti Trivelli, Senator of the Kingdom of Italy, niece of Gioacchino Murat and Carolina Bonaparte (Napoleon's sister), purchased the land across from the gardens of the Quirinal Palace, where the house of Tito Pomponio Attico, editor and friend of Cicero, once stood. She entrusted the task of building Villa Spalletti Trivelli to Architect Domenico Avenali (who availed of expert artists and artisans, like Edoardo Gioja).
Thanks to the vision of Countess Rasponi, President of the National Council of Italian Women, Villa Spalletti Trivelli became an important political and cultural meeting place. Every Thursday afternoon, the influential figures of the time frequented the villa’s drawing rooms. This included the likes of Romualdo Bonfaldini, Sidney Sonnino and Rabindranath Tagore, the Nobel Prize winner in Literature in 1913.
In the early 1930s, Cesare Spalletti Trivelli inherited the historic residence in downtown Rome from his mother where he would then live with his wife, Countess Guendalina Cavazzi della Somaglia. Respectively made a Gentleman and Lady of the Court of Queen Marie José of Belgium (wife of Umberto II of Savoia, the last King of Italy), the count and countess would then leave the villa to their son, Piero, a sensitive writer and refined poet.
In 2004, Giangiacomo Spalletti Trivelli, son of Count Piero, and his wife, Susanna, daughter of horseback riding champion Raimondo d'Inzeo, decided to convert the family's historic residence into an exclusive luxury residence for the more refined and demanding travellers.